You see number 5 goes right along with this page: Evolution, conform or fail (link). The guy basically leaves you no other way to believe (conformism). And by the way, conformism is not science.
But let’s look at an example of what changing the number of chromosome can do. Down Syndrome (link) is caused by the presence of an extra chromosome. You see the evolutionists are betting that you won’t go do the research to find if what they claim about evolution is true. And what we find about doing anything with the chromosomes that is different from the norm causes all kinds of problems including death.
When the chromosome’s structure is altered. This can take several forms:
1) Deletions: A portion of the chromosome is missing or deleted. Known disorders in humans include Wolf-Hirschhorn syndrome, which is caused by partial deletion of the short arm of chromosome 4; and Jacobsen syndrome, also called the terminal 11q deletion disorder.
2) Duplications: A portion of the chromosome is duplicated, resulting in extra genetic material. Known human disorders include Charcot-Marie-Tooth disease type 1A which may be caused by duplication of the gene encoding peripheral myelin protein 22 (PMP22) on chromosome 17.
3) Translocations: When a portion of one chromosome is transferred to another chromosome. There are two main types of translocations. In a reciprocal translocation, segments from two different chromosomes have been exchanged. In a Robertsonian translocation, an entire chromosome has attached to another at the Centromere – in humans these only occur with chromosomes 13, 14, 15, 21 and 22.
4) Inversions: A portion of the chromosome has broken off, turned upside down and reattached, therefore the genetic material is inverted.
5) Rings: A portion of a chromosome has broken off and formed a circle or ring. This can happen with or without loss of genetic material.
6) Isochromosome: Formed by the mirror image copy of a chromosome segment including the centromere.
Chromosome instability syndromes are a group of disorders characterized by chromosomal instability and breakage. They often lead to an increased tendency to develop certain types of malignancies.
Reference: Wikipedia (link).
So basically there is not even one good example of changing Chromosome numbers. So the claim about Chromosome #2 is just a bunch of evolutionists desperate to prove a theory.